Molecular Mediators Governing Iron-Copper Interactions
نویسندگان
چکیده
منابع مشابه
The molecular basis of copper and iron interactions.
The intimate relationship between Fe and Cu in human nutrition has been recognised for many years. The best-characterised link is provided by caeruloplasmin, a multiCu-binding protein that acts as a serum ferrioxidase and is essential for the mobilisation of Fe from storage tissues. Decreased Cu status has been shown to reduce holo-caeruloplasmin production and impair ferrioxidase activity, lea...
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Whereas neural crest cells are the source of the peripheral nervous system in the trunk of vertebrates, the "ectodermal placodes," together with neural crest, form the peripheral nervous system of the head. Cranial ectodermal placodes are thickenings in the ectoderm that subsequently ingress or invaginate to make important contributions to cranial ganglia, including epibranchial and trigeminal ...
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During development, the fetus is entirely dependent on the mother for its nutrient requirements. Subsequently, it is a period when both are vulnerable to changes in dietary supply, especially of those nutrients that are marginal under normal circumstances. In developed countries, this applies mainly to micronutrients. Even now, iron deficiency is a common disorder, especially in pregnancy. Simi...
متن کاملIron , zinc , copper and
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Microminerals including copper and iron are essential to immunity and health in human beings. The development of powerful tools in analytical cell biology and molecular genetics has facilitated efforts to identify specific cellular and molecular functions of trace elements in the maturation, activation and functions of host defence mechanisms. Selected recent reports about the role of copper an...
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ژورنال
عنوان ژورنال: Annual Review of Nutrition
سال: 2014
ISSN: 0199-9885,1545-4312
DOI: 10.1146/annurev-nutr-071812-161215